Abstract Background Epithelial mesenchymal transition (EMT) is tightly regulated by a network of transcription factors (EMT-TFs).Among them is the nuclear factor ZEB2, a member of the zinc-finger E-box binding homeobox family.ZEB2 nuclear localization has been identified in several cancer types, and its overexpression is correlated with the maligna
SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolism and mitochondrial function.SIRT3 activates several mitochondrial enzymes, SIRT4 represses Optical Media its targets, and SIRT5 has been shown to both activate and repress mitochondrial enzymes.To gain insight into the relative effects of the mitoch
Abstract Supply chain management has shown to be an aspect of construction that is neglected, yet with great impact on project delivery time frames and the overall cost Optical Media of construction projects.This research seeks to identify, assess, and propose solutions for the challenges hindering the adoption of digital technologies in constructi
Summary: MicroRNAs (miRNAs) are transcribed as long primary transcripts (pri-miRNAs) by RNA polymerase II.Plant pri-miRNAs encode regulatory peptides called miPEPs, which specifically enhance Yoga the transcription of the pri-miRNA from which they originate.However, paradoxically, whereas miPEPs have been identified in different plant species, they